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Exploring the SPIDER Framework: A Qualitative Research Tool Beyond PICO for Systematic Reviews and Evidence Syntheses
Understanding the SPIDER Framework and Its Benefits for Qualitative Research
What is the SPIDER Framework and How Does It Enhance Qualitative Research?
- The SPIDER framework is a structured approach used in qualitative research to guide the formulation of research questions and search strategies. This framework was developed by Alison Cooke, Debbie Smith, and Andrew Booth.
- It is designed to support systematic reviews and evidence syntheses by focusing on qualitative studies rather than quantitative methods.
- The SPIDER framework stands for Sample, Phenomenon of Interest, Design, Evaluation, and Research Type. This allows researchers to focus on the specifics of qualitative research questions, ensuring that the search tools and strategies used are aligned with qualitative methods.
- By using the SPIDER framework, researchers can develop a more sensitive and specific search strategy, essential for finding relevant studies. The framework helps define the key elements of a research question, making it a valuable tool for both systematic reviews of interventions and qualitative research.
- The SPIDER framework is especially helpful for those working in evidence-based practice (EBP), as it aids in identifying the phenomenon of interest and refining the search for qualitative articles or mixed-methods research.
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Comparing SPIDER with PICO: Key Differences and Advantages
- The SPIDER framework differs from the PICO tool, primarily in its focus on qualitative research rather than the more commonly used quantitative research model.
- While PICO focuses on Patient, Intervention, Comparison, and Outcome, the SPIDER framework emphasizes the need to focus on the specificity of qualitative studies, defining the phenomenon of interest and the research type more clearly.
- The SPIDER framework offers a more flexible search strategy for qualitative research by considering study designs, such as qualitative, mixed-methods, and comparative studies. In contrast, PICO is more rigid and suited for quantitative research or systematic reviews of interventions.
- Using SPIDER and PICO together can offer a comprehensive approach for systematic search strategies that include both qualitative and quantitative studies.
The Role of the SPIDER Framework in Formulating a Qualitative Research Question
- The SPIDER framework is essential in formulating a research question for qualitative studies. It helps to clearly define key elements like the sample, phenomenon of interest, and design, making it easier for researchers to focus their search on the most relevant data.
- By focusing on research type, the SPIDER framework ensures that the search strategy is tailored for qualitative articles, which is crucial for an effective systematic search in electronic databases like Embase and Cochrane handbook for systematic reviews.
- The SPIDER framework also helps define a study design that is appropriate for qualitative research, considering specificity and sensitivity in search tools used by qualitative researchers. This can improve the effectiveness of the search process and ensure that results align with evidence-based practice.
- When using the SPIDER framework, the process is more flexible and adaptable than traditional PICO searches, ensuring that qualitative studies are evaluated using search strategies that account for the nuances of qualitative and mixed-method research.
| Aspect | SPIDER Framework | PICO Framework |
| Full Form | Sample, Phenomenon of Interest, Design, Evaluation, Research Type | Patient, Intervention, Comparison, Outcome |
| Focus | Primarily used for qualitative research | Primarily used for quantitative research |
| Research Type | Qualitative and mixed-methods research | Quantitative research, especially clinical trials and interventions |
| Sample | Defines the participants or groups to study (e.g., individuals, communities) | Defines the target patient population (e.g., adults with hypertension) |
| Phenomenon of Interest | Describes the central issue or concept being explored (e.g., experiences, behaviours) | Describes the condition or problem under study (e.g., hypertension) |
| Design | Focuses on qualitative designs such as case studies, ethnography, grounded theory | Focuses on experimental or observational designs, such as RCTs |
| Evaluation | How data is collected and analysed in qualitative research (e.g., thematic analysis) | How outcomes are measured (e.g., blood pressure reduction, recovery rate) |
| Research Type | Specifies the qualitative or mixed-methods approach | Specifies experimental or observational study types |
| Example Research Question | “How do healthcare professionals perceive the effectiveness of telemedicine in remote areas?” | “In adults with hypertension, how does the use of a low-salt diet compared to medication affect blood pressure?” |
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Practical Tips for Formulating Qualitative Research Questions Using the SPIDER Framework
Key Elements to Consider When Using the SPIDER Framework for Research Questions
- The SPIDER framework is designed to help researchers formulate clear and focused qualitative research questions by considering five key elements:
- Sample: Determine who or what will be studied (e.g., a specific group of individuals or communities). This helps define the research’s scope.
- Phenomenon of Interest: Clearly identify what the study aims to explore or understand. This is the central issue that guides the study, whether it’s behaviours, experiences, or perceptions.
- Design: Choose the most appropriate qualitative study design, such as case studies, grounded theory, or ethnography. This step ensures that the study’s methodology aligns with the research question.
- Evaluation: Define how data will be analysed, focusing on qualitative methods such as thematic analysis or narrative analysis. This is essential for deriving meaningful insights from qualitative data.
- Research Type: Specify the research type (qualitative, mixed-methods, or quantitative). Qualitative research often requires different search strategies compared to quantitative studies, influencing the use of search tools and indexing of qualitative studies.
How to Effectively Use SPIDER for Abstract and Search Terms Formulation
- Search Tools for Qualitative Research: When formulating research questions using the SPIDER framework, it’s essential to use appropriate search tools for qualitative systematic reviews. This includes databases like Embase, Cochrane, and PsycINFO, which specialise in qualitative studies.
- Develop a list of keywords from the SPIDER framework components. For example, terms like sample, phenomenon of interest, and study design should be included in your search queries.
- Ensure your abstract captures the key elements of the SPIDER framework. This will enhance your study’s visibility and ensure it is indexed properly for future research.
- Alternative Search Strategies: Explore alternative search methods for qualitative and mixed-methods research, ensuring you include terms related to qualitative research types. These strategies increase the chances of finding relevant studies when using the SPIDER framework.

Expert Advice on Creating Specific and Actionable Qualitative Research Questions
- Focus on specificity when formulating your research question. Use the SPIDER framework to clearly define the phenomenon of interest. Avoid broad or vague questions, as they can lead to irrelevant results.
- For example, instead of asking “How do people experience health?”, narrow it down to “How do healthcare professionals perceive the impact of technology on patient care?”
- Incorporate sensitivity in the search tools used. The sensitivity in three search tools method helps identify studies that closely align with the phenomenon of interest. By focusing on highly sensitive tools, researchers can capture more specific results, especially for qualitative studies.
- Apply the PICO approach for comparison when relevant, especially in mixed-method studies. For instance, PICOS and SPIDER can be combined for comparison studies, enhancing the precision of your systematic reviews.
- Make your research questions actionable. They should provide clear direction on how to proceed with data collection and analysis, ensuring the study remains focused on its intended outcomes.
By applying the SPIDER framework, researchers can develop qualitative research questions that are specific, focused, and actionable. This structured approach enhances the precision of search strategies, increasing the likelihood of retrieving relevant studies that contribute to evidence-based practice and improving healthcare outcomes.
Integrating SPIDER Framework in Mixed Methods and Evidence Synthesis
Leveraging SPIDER for Formulating a Mixed Methods Research Question
- The SPIDER framework can be highly effective in mixed-methods research by helping to formulate research questions that combine qualitative and quantitative approaches.
- When using the SPIDER framework for mixed methods, consider the following elements:
- Sample: Identify both qualitative and quantitative samples, considering the need for both depth (qualitative) and breadth (quantitative).
- Phenomenon of Interest: Define what will be studied across both methods—this could be a complex issue requiring both qualitative insights and quantitative measurement.
- Design: Use the SPIDER framework to structure both qualitative and quantitative study designs, ensuring coherence between them.
- Evaluation: In a mixed methods study, define both qualitative and quantitative methods for evaluating the findings.
- Research Type: Specify the research type (qualitative and quantitative), ensuring that both research elements are integrated seamlessly into the final research question.
- The SPIDER framework allows for greater specificity and clarity when formulating mixed-methods research questions, ensuring both types of data complement each other, leading to a more comprehensive understanding of the research topic.
| Question Type | Sample | Phenomenon of Interest | Design | Evaluation | Research Type |
| Therapy | Elderly patients with dementia | Effectiveness of cognitive therapy | Qualitative study (e.g., interviews, focus groups) | Patient’s perceived cognitive improvement | Qualitative research |
| SPIDER Research Question: In elderly patients with dementia, how do they perceive the effectiveness of cognitive therapy compared to standard medication? | |||||
| Diagnosis | Adults with chronic fatigue syndrome | Psychological factors in chronic fatigue | Ethnographic study | Impact on daily life activities | Qualitative research |
| SPIDER Research Question: In adults with chronic fatigue syndrome, how do psychological factors influence their daily activities and quality of life? | |||||
| Prognosis | Post-operative cancer patients | Post-surgery recovery challenges | Case study | Recovery rate based on psychosocial support | Qualitative research |
| SPIDER Research Question: In post-operative cancer patients, how do psychosocial factors influence their recovery and well-being? | |||||
| Etiology or Harm | Smokers with respiratory issues | Perceptions of smoking-related health risks | Grounded theory study | Changes in health behaviours post-intervention | Mixed-methods research |
| SPIDER Research Question: In smokers with respiratory issues, how do perceptions of smoking-related health risks affect their willingness to quit smoking? | |||||
| Prevention | Overweight adolescents | Impact of family support on weight loss | Phenomenological study | Success of weight loss efforts based on family support | Qualitative research |
| SPIDER Research Question: In overweight adolescents, how does family support influence the effectiveness of weight loss efforts compared to those with no family support? | |||||
Enhancing Evidence Synthesis with SPIDER in Qualitative Research
- Evidence synthesis in qualitative research can benefit greatly from the SPIDER framework by improving how qualitative studies are selected and analysed.
- Use the SPIDER framework to guide search strategies when performing literature reviews or systematic reviews of qualitative studies.
- Incorporate the three search tools for qualitative research such as Embase, Cochrane, and PsycINFO to search for studies based on the key components of the SPIDER framework (e.g., sample, phenomenon, design).
- When conducting a comparison study of specificity, the SPIDER framework helps focus on the most relevant studies, allowing researchers to synthesise findings more accurately.
- By enhancing sensitivity and specificity in three search tools, the SPIDER framework ensures that the evidence synthesis includes the most relevant and high-quality qualitative studies, improving the reliability of the research synthesis.
- Here is an example of literature search strategy developed using the SPIDER framework.
Best Practices for Using SPIDER Framework in Qualitative and Mixed Methods Studies
- To effectively use the SPIDER framework in qualitative and mixed-methods research, follow these best practices:
- Define key elements early: Clearly define the sample, phenomenon of interest, design, evaluation, and research type using the SPIDER framework. This ensures that all components align with the research goal.
- Combine PICO with SPIDER: The SPIDER framework can complement the PICO tool in mixed methods studies, especially when there is a need to integrate qualitative and quantitative data.
- Use specific search strategies: Employ a focused search strategy that uses terms from the SPIDER framework to guide database searches for qualitative studies, improving the searching strategy.
- Collaborate with health care professionals: The SPIDER framework can guide researchers in forming research questions that are relevant to the real-world challenges faced by health care professionals or those in allied health, ensuring practical and evidence-based outcomes.
- Assess specificity and sensitivity: Evaluate your search tools for their sensitivity and specificity in finding relevant qualitative studies. Adjust your search strategy if necessary to ensure more accurate and actionable findings.
By integrating the SPIDER framework, researchers can enhance the precision of qualitative research and mixed-methods studies, improving both the search strategies and evidence synthesis processes. This structured approach ensures that research findings are relevant and valuable to evidence-based practice (EBP) and can significantly impact the quality of healthcare outcomes.